145 articles

The dangers of commercial direct-to-consumer tests

Lifestyle tests that pretend to be medical procedures are inherently problematic in terms of clinical, medical and privacy issues. Professor Matthias Orth, Medical Director of the Institute of Laboratory Medicine at Marienhospital Stuttgart, discussed ‘Direct-to-consumer ...

01/09/2017

Scientists tissue-engineer part of human stomach

Researchers at Cincinnati Children’s Hospital Medical Center grew functional stomach and intestinal tissues to study diseases and new drugs. They use pluripotent stem cells to generate human stomach tissues in a petri dish that produce acid and digestive enzymes.

01/06/2017

Molecular Roots of Alzheimer’s

Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer’s disease. Knowing the shape of the molecule — and how that shape may be disrupted by certain genetic mutations — can help in ...

12/22/2016

Neural stem cells found in brain of epilepsy patients

Neural stem cells have been found in epileptic brain tissue - outside the regions of the brain where they normally reside. In a group of patients who underwent surgery for epilepsy, over half had stem cells where healthy individuals do not have them, according to a study from ...

12/22/2016

Genetic testing cannot determine antimicrobial susceptibility

Experts at the European Committee on Antimicrobial Susceptibility Testing (EUCAST), who define the optimal drug concentrations to inhibit the growth of pathogens, have found that genetic methods cannot yet be used to test for susceptibility in a number of important bacterial ...

12/12/2016

A gene that limits desire to drink alcohol

In the largest study of its kind, UT Southwestern Medical Center researchers and colleagues in Europe identified a gene variant that suppresses the desire to drink alcohol.

12/06/2016

Genetic model of common infant leukemia described

After nearly two decades of unsuccessful attempts, researchers from the University of Chicago Medicine and the Cincinnati Children’s Hospital Medical Center have created the first mouse model for the most common form of infant leukemia. Their discovery could hasten development ...

11/29/2016

Predicting a response to treatment in patients with lung cancer

Menarini-Silicon Biosystems announced the company’s DEPArray single-cell isolation technology played a key role in a study conducted by researchers from The University of Manchester to develop a model for predicting whether small-cell lung cancer patients will be sensitive or ...

11/28/2016

Friendly Fire in the Pancreas

n type 1 diabetes, the body attacks its own insulin-producing cells. Scientists at Helmholtz Zentrum München, partner in the German Center for Diabetes Research, and their colleagues at Technical University of Munich have now reported in the journal ‘PNAS’ about a mechanism ...

10/31/2016

Brain cell ‘executioner’ identified

Despite their different triggers, the same molecular chain of events appears to be responsible for brain cell death from strokes, injuries and even such neurodegenerative diseases as Alzheimer's. Now, researchers at Johns Hopkins say they have pinpointed the protein at the end ...

10/14/2016