Genetics

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News • BRCA1 and BRCA2 malfunctions

Targeting 'exhausted' immune cells to prevent breast cancer

A study found immune cells in breast tissue of healthy women carrying BRCA1 or BRCA2 gene mutations show signs of ‘exhaustion’. This opens new possibilities for cancer prevention.

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News • Characterization of cancer relevant genes

Breast cancer: Researchers take a deep dive into cell lines

Biochemists and bioinformaticians from the Leibniz Institute DSMZ have extensively characterized the molecular properties of the breast cancer cell lines from the institute's collection.

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News • Neurodegeneration

New insights on cause of brain calcification

Much like joints or blood vessels, the brain can be affected by calcifications. This can lead to neurodegenerative disease, but is not well studied. Now, researchers from Norway identified a gene…

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News • Mammacarcinoma research

Study pinpoints breast cancer ‘cells-of-origin’ in high-risk women

Scientists have pinpointed likely ‘cells-of-origin’, the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.

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News • Promising study in mice

Exploring the potential of mRNA technology for rare diseases

Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.

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News • Finding therapy-relevant genetics

Leukaemia: AI provides support in diagnostics

Certain genetic features are crucial for treatment decisions for AML leukaemia. A team from Münster shows how an AI-based method can predict these features from images of bone marrow smears.

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News • Promising application of "gene scissors"

Using CRISPR-Cas9 to treat anaemia

ETH Zurich molecular biologist Mandy Boontanrart is researching gene therapies that could be used to cure two of the most common types of inherited anaemia: beta thalassaemia and sickle cell anaemia.

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