A European team of researchers have successfully developed a new, living organ model which could advance rapid testing of new or common drugs to treat diseases of the liver.
A research team from Barcelona studied the liver of Alzheimer's disease mice models, and demonstrated the importance of the liver-brain axis regarding the psychological symptoms of the disease.
Omar Darwish, PhD student at King's College London, is researching new approaches to 3D MRE sequences for measuring liver fibrosis and inflammation simultaneously in obese patients.
A pioneering new method to assess the quality of organs for donation has the potential to revolutionise the transplant system, saving lives and tens of millions of pounds.
Dutch physicians have developed a system to determine the right dose of immunosuppressive drugs for patients to receive a donor liver - to prevent the activation of the Epstein-Barr virus.
To assess diffuse liver disease, MRI is currently the modality of choice. New developments in artificial intelligence (AI) could tip the scales in favour of CT imaging. At ECR 2022 in July, experts showed how AI technology enables CT to quantify liver fat as exquisitely as MRI.
Treating liver cancer tumours to shrink them in order to allow the patient to qualify for a liver transplant leads to excellent 10-year post-transplant outcomes, according to new research.
Newly engineered in vitro tumour models open ways to better understand the crosstalk between liver cancer cells and their microenvironment, researchers from Singapore found.
The research team Liver4Life has treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.
Scientists have identified a new disease in a ground-breaking discovery that could help patients with unexplained liver and kidney problems.
Scientists from France and Belgium gained insights into the structure and function of a central liver protein: NTCP, a cellular-entry pathway for bile salts – but also for certain hepatitis viruses.
An international research team has now found an approach to lower the activation of hepatic stellate cells (HSCs) and reduce the associated development of liver fibrosis.
A platform for studying how the human immune system responds to hepatitis C infection by combining microfluidic technology with liver organoids could speed the hunt for a vaccine.
Scientists have investigated the effectiveness of various common hand disinfectants against hepatitis E. They were able to show that most formulations do not completely inactivate the virus.
Even as we battle one pandemic (Covid-19), we sit on the cusp of another. Europe has one of the highest burdens of chronic liver disease (CLD) in the world, driven largely by alcohol overconsumption, viral hepatitis, and obesity. Furthermore, non-alcoholic fatty liver disease (NAFLD) is increasingly common and is a significant contributor to CLD – especially in people with diabetes, where its…
Professor Dina Tiniakos, from the National and Kapodistrian University of Athens, predicts that NASH (Non-alcohol related steatohepatitis) cases will soar worldwide by 2030, with 800,000 liver deaths, costing health economies billions of dollars.
Autoimmune hepatitis (AIH) is a chronic liver inflammation that is triggered by an immunological malfunction. In this case, the immune system falsely recognises the patient's own liver cells as "foreign to the body". The symptoms of this rare liver disease are unspecific, and the exact cause is not yet known. If left untreated, AIH can lead to abnormal scarring (fibrosis) of the liver,…
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in western countries, with an increasing incidence worldwide. Consequences of NAFLD can also include kidney disease and kidney stones, although the mechanisms for the development of these kidney complications as a result of NAFLD have not yet been fully explained. Researchers at the Leibniz Research Centre for Working…
With the application of a novel 3D imaging technology, researchers at Karolinska Institutet have discovered that one portion of the autonomic nervous system in the liver undergoes severe degeneration in non-alcoholic fatty liver disease. The study, which is conducted in mice and human liver tissue, shows that the degeneration of nerves is correlated with the severity of liver pathology. The…
